Sandbox Reserved 1654: Difference between revisions
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* A N-terminal region which is a regulatory region with phosphorylation and dephosphorylation sites. This region is variable in length and composition. | * A N-terminal region which is a regulatory region with phosphorylation and dephosphorylation sites. This region is variable in length and composition. | ||
* A C-terminal region, composed of 2 recognition patterns (RRMs which allow a good positioning of RNA, a high fidelity and are essential for the CPE specific recognition) and 2 zinc finger patterns (containing two zinc binding sites and a specific RNA-binding protein sequence which play a role in affinity but not in specificity). | * A C-terminal region, composed of 2 recognition patterns (RRMs which allow a good positioning of RNA, a high fidelity and are essential for the CPE specific recognition) and 2 zinc finger patterns (containing two zinc binding sites and a specific RNA-binding protein sequence which play a role in affinity but not in specificity). | ||
** Zinc finger patterns | ** Zinc finger patterns | ||
<StructureSection load='2m13' size='340' side=' | <StructureSection load='2m13' size='340' side='left' caption='Caption for this structure' scene=''> | ||
</StructureSection> | </StructureSection> | ||
About 54 residues with 6 cysteines and 2 histidines, conserved for all isoforms and species. The modification of one of the eight zinc ligands destabilize the connection to the mRNA. The domain includes : | About 54 residues with 6 cysteines and 2 histidines, conserved for all isoforms and species. The modification of one of the eight zinc ligands destabilize the connection to the mRNA. The domain includes : | ||
