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==Crystal structure of human F508A NBD1 domain with ATP==
==Crystal structure of human F508A NBD1 domain with ATP==
<StructureSection load='1xmi' size='340' side='right' caption='[[1xmi]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
<StructureSection load='1xmi' size='340' side='right'caption='[[1xmi]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1xmi]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XMI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XMI FirstGlance]. <br>
<table><tr><td colspan='2'>[[1xmi]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XMI OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1XMI FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1xmj|1xmj]], [[1q3h|1q3h]], [[1r0w|1r0w]], [[1r0x|1r0x]], [[1r0y|1r0y]], [[1r0z|1r0z]], [[1r10|1r10]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1xmj|1xmj]], [[1q3h|1q3h]], [[1r0w|1r0w]], [[1r0x|1r0x]], [[1r0y|1r0y]], [[1r0z|1r0z]], [[1r10|1r10]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CFTR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CFTR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Channel-conductance-controlling_ATPase Channel-conductance-controlling ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.49 3.6.3.49] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Channel-conductance-controlling_ATPase Channel-conductance-controlling ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.49 3.6.3.49] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xmi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xmi OCA], [http://pdbe.org/1xmi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xmi RCSB], [http://www.ebi.ac.uk/pdbsum/1xmi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1xmi ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1xmi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xmi OCA], [http://pdbe.org/1xmi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xmi RCSB], [http://www.ebi.ac.uk/pdbsum/1xmi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1xmi ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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==See Also==
==See Also==
*[[ABC transporter|ABC transporter]]
*[[ABC transporter 3D structures|ABC transporter 3D structures]]
*[[Ion channels|Ion channels]]
== References ==
== References ==
<references/>
<references/>
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[[Category: Channel-conductance-controlling ATPase]]
[[Category: Channel-conductance-controlling ATPase]]
[[Category: Human]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Condon, B]]
[[Category: Condon, B]]
[[Category: Conners, K]]
[[Category: Conners, K]]
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