Sandbox Reserved 1653: Difference between revisions
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==='''CTD and Beam'''=== | ==='''CTD and Beam'''=== | ||
CTD and <scene name='86/868186/Beam_1_couleurs/1'>beams</scene> are intracellular. The beam interacts with the CTD, and both are required for mechanical activation of the channel. (architecture) | CTD and <scene name='86/868186/Beam_1_couleurs/1'>beams</scene> are intracellular. The beam interacts with the CTD, and both are required for mechanical activation of the channel. (architecture)<ref name="architecture"/> | ||
The <scene name='86/868186/Ctd_trimeric/1'>CTD</scene> is a trimeric structure and is a part of the pore module of piezo channel. The CTD interacts with the long <scene name='86/868186/Anchor/1'>anchorα</scene>, and forms a hydrophobic interface. This forms a tripartite interaction with the <scene name='86/868186/E_dans_ctd/1'>glutamate-rich regions of the CTD</scene> (mechanogating)<ref name="mechanogating"> DOI 10.1038/nature25743 </ref> | The <scene name='86/868186/Ctd_trimeric/1'>CTD</scene> is a trimeric structure and is a part of the pore module of piezo channel. The CTD interacts with the long <scene name='86/868186/Anchor/1'>anchorα</scene>, and forms a hydrophobic interface. This forms a tripartite interaction with the <scene name='86/868186/E_dans_ctd/1'>glutamate-rich regions of the CTD</scene> (mechanogating)<ref name="mechanogating"> DOI 10.1038/nature25743 </ref> | ||
It forms an intracellular vestibule along the z-axis, and it is essential for ion permeation properties. More precisely, the pore module of | It forms an intracellular vestibule along the z-axis, and it is essential for ion permeation properties. More precisely, the pore module of | ||
