Sandbox Reserved 1654: Difference between revisions
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== Function == | == Function == | ||
CPEB controls the balance between senescence and proliferation. Indeed, due to its two structural domains in its C-terminal region, it has the capacity to modify mRNA[2]. | CPEB controls the balance between senescence and proliferation. Indeed, due to its two structural domains in its C-terminal region, it has the capacity to modify mRNA<up>[2]</up>. | ||
RRMs domains allow binding to the CPE sequence of mRNA (pyrimidine rich : UUUUUAU), thus ensuring good RNA positioning and high fidelity. | RRMs domains allow binding to the CPE sequence of mRNA (pyrimidine rich : UUUUUAU), thus ensuring good RNA positioning and high fidelity. | ||
Zing finger domains allow binding to different proteins, which play a role in affinity but not in specificity. It's therefore its ability to recruit different proteins that will determine its action, activation or repression of translation. | Zing finger domains allow binding to different proteins, which play a role in affinity but not in specificity. It's therefore its ability to recruit different proteins that will determine its action, activation or repression of translation. | ||
