Sandbox Reserved 1660: Difference between revisions
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=== Role in the immune system === | === Role in the immune system === | ||
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3GMQ protein is a molecule of the immune system. It is involved in presenting a lipidic antigen to NKT cells. Indeed, these proteins are located on the surface of the plasma membrane of APC. When the recognition between the CD1d bound to its lipidic ligand and the TCR of a NKT cell occurs, the lymphocyte turns out to be activated. Thus, the production of cytotoxic molecules such as Th1, Th2, interleukin-4 and INF-gamma is triggered by this activation. | |||
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=== Ligands presented by CD1d === | === Ligands presented by CD1d === | ||
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The ligands of CD1d protein are very specific. Only a narrow set of molecules can bind its recognition site. Amongst those molecules are aplhaGalCer, alpha glucuronyl ceramide acid, alpha galacturonyl ceramide acid, IGb3 and HS44. | |||
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== Structure == | == Structure == | ||
