Sandbox Reserved 1660: Difference between revisions

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~~3GMQ~~ protein is a molecule of the immune system. It is involved in presenting a lipidic antigen to NKT cells. Indeed, these proteins are located on the surface of the plasma membrane of APC. When the recognition between the CD1d bound to its lipidic ligand and the TCR of a NKT cell occurs, the lymphocyte turns out to be activated. Thus, the production of cytotoxic molecules such as Th1, Th2, interleukin-4 and INF-gamma is triggered by this activation.

CD1d protein is a molecule of the immune system. It is involved in presenting a lipidic antigen to NKT cells. Indeed, these proteins are located on the surface of the plasma membrane of APC. When the recognition between the CD1d bound to its lipidic ligand and the TCR of a NKT cell occurs, the lymphocyte turns out to be activated. Thus, the production of cytotoxic molecules such as Th1, Th2, interleukin-4 and INF-gamma is triggered by this activation.

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Additionally, there are two oligosaccharides bound to the alpha chain via N-glycosylations and three types of small molecules bound to that protein. ~~The overall structure of~~ CD1d ~~protein is akin~~ to class I ~~MHC’s molecules. Notwithstanding~~, the cleft where the ligand can bind its protein is different between MHC molecules and CD1d molecules. Indeed, the hydrophobic cleft of CD1d has a narrow opening.

Additionally, there are two oligosaccharides bound to the alpha chain via N-glycosylations and three types of small molecules bound to that protein. CD1d molecules are structurally similar to MHC class I, but present lipid antigens as opposed to peptides and the cleft where the ligand can bind its protein is different between MHC molecules and CD1d molecules. Indeed, the hydrophobic cleft of CD1d has a narrow opening.

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Sandbox Reserved 1660: Difference between revisions

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@@ Line 18: / Line 18: @@
 <p align="justify">
-GMQ protein is a molecule of the immune system. It is involved in presenting a lipidic antigen to NKT cells. Indeed, these proteins are located on the surface of the plasma membrane of APC. When the recognition between the CD1d bound to its lipidic ligand and the TCR of a NKT cell occurs, the lymphocyte turns out to be activated. Thus, the production of cytotoxic molecules such as Th1, Th2, interleukin-4 and INF-gamma is triggered by this activation.
+CD1d protein is a molecule of the immune system. It is involved in presenting a lipidic antigen to NKT cells. Indeed, these proteins are located on the surface of the plasma membrane of APC. When the recognition between the CD1d bound to its lipidic ligand and the TCR of a NKT cell occurs, the lymphocyte turns out to be activated. Thus, the production of cytotoxic molecules such as Th1, Th2, interleukin-4 and INF-gamma is triggered by this activation.
 </p>
@@ Line 37: / Line 37: @@
 <p align="justify">
-Additionally, there are two oligosaccharides bound to the alpha chain via N-glycosylations and three types of small molecules bound to that protein. The overall structure of CD1d protein is akin to class I MHC’s molecules. Notwithstanding, the cleft where the ligand can bind its protein is different between MHC molecules and CD1d molecules. Indeed, the hydrophobic cleft of CD1d has a narrow opening.
+Additionally, there are two oligosaccharides bound to the alpha chain via N-glycosylations and three types of small molecules bound to that protein. CD1d molecules are structurally similar to MHC class I, but present lipid antigens as opposed to peptides and the cleft where the ligand can bind its protein is different between MHC molecules and CD1d molecules. Indeed, the hydrophobic cleft of CD1d has a narrow opening.
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