Sandbox Reserved 1660: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 24: | Line 24: | ||
<p align="justify"> | <p align="justify"> | ||
The ligands | The ligands that can be presented by CD1d to NKT or other CD1d-restricted T cells are very specific. Only a narrow set of molecules can bind its recognition site. These include glycolipids from a marine sponge, bacterial glycolipids, normal endogenous glycolipids, tumor-derived phospholipids and glycolipids, and nonlipidic molecules. | ||
</p> | </p> | ||
| Line 56: | Line 56: | ||
==== Immunotherapeutic tool ==== | ==== Immunotherapeutic tool ==== | ||
<p align="justify"> | |||
The presentation of many of ligands can have immunopotentiating effects, such as serving as an adjuvant against malaria or resulting in a more rapid clearance of certain virus infections. They can also be protective in autoimmune diseases or cancer. | |||
</p> | |||
==== NKT cells marker ==== | ==== NKT cells marker ==== | ||
