Sandbox Reserved 1648: Difference between revisions

Revision as of 13:16, 13 January 2021 view source Clarisse Poisson (talk \| contribs) 38 edits No edit summary ← Older edit		Revision as of 16:35, 13 January 2021 view source Léane Costa-Roch (talk \| contribs) 67 edits No edit summary Newer edit →
Line 56:		Line 56:

	== '''Signaling pathways''' ==		== '''Signaling pathways''' ==
	The leptin receptor has cytokine receptor characteristics. The transduction of the signal by this type of receptor involves the formation of multimeric complexes. This leads to the recruitment of tyrosine kinases, in particular those of the JAK family, which will phosphorylate STAT-like transcription factors at the cytoplasmic tail of the receptor. Recruitment and activation of secondary signalling molecules enable the ~~lept~~ signalling via the MAPK, PI3K, AMPK and mTOR pathways.		The leptin receptor has cytokine receptor characteristics. The transduction of the signal by this type of receptor involves the formation of multimeric complexes. This leads to the recruitment of tyrosine kinases, in particular those of the JAK family, which will phosphorylate STAT-like transcription factors at the cytoplasmic tail of the receptor. Recruitment and activation of secondary signalling molecules enable the leptin receptor signalling via the MAPK, PI3K, AMPK and mTOR pathways.

Navigation menu