Sandbox Reserved 1660: Difference between revisions
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CD1d protein is a molecule of the [https://en.wikipedia.org/wiki/Immune_system immune system]. It is involved in presenting a lipidic antigen to NKT cells. Indeed, these proteins are located on the surface of the plasma membrane of [https://en.wikipedia.org/wiki/Antigen-presenting_cell APC cells]. When the recognition between the CD1d bound to its lipidic ligand and the TCR of a NKT cell occurs, the lymphocyte turns out to be activated. Thus, the production of cytotoxic molecules such as Th1, Th2, interleukin-4 and INF-gamma is triggered by this activation. Therefore, CD1d proteins are precursors of the adaptive immune reaction which are key activators of the NKT cells. As a result, a deficiency of CD1d proteins may lead to a deficiency of the NKT cells functioning and thus to autoimmune diseases and cancers. | CD1d protein is a molecule of the [https://en.wikipedia.org/wiki/Immune_system immune system]. It is involved in presenting a lipidic antigen to NKT cells. Indeed, these proteins are located on the surface of the plasma membrane of [https://en.wikipedia.org/wiki/Antigen-presenting_cell APC cells]. When the recognition between the CD1d bound to its lipidic ligand and the [[TCR]] of a NKT cell occurs, the lymphocyte turns out to be activated. Thus, the production of cytotoxic molecules such as Th1, Th2, interleukin-4 and INF-gamma is triggered by this activation. Therefore, CD1d proteins are precursors of the adaptive immune reaction which are key activators of the NKT cells. As a result, a deficiency of CD1d proteins may lead to a deficiency of the NKT cells functioning and thus to autoimmune diseases and cancers. | ||
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