Sandbox Reserved 1661: Difference between revisions
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== Somatotropin and Genetic origin == | == Somatotropin and Genetic origin == | ||
Somatotropin (GH for ''Growth Hormone'' or HGH for ''Human Growth Hormone'') is a polypeptide hormone produced by the [https://en.wikipedia.org/wiki/Somatotropic_cell somatotropic cells] of the [https:// | Somatotropin (GH for ''Growth Hormone'' or HGH for ''Human Growth Hormone'') is a polypeptide hormone produced by the [https://en.wikipedia.org/wiki/Somatotropic_cell somatotropic cells] of the [https://www.britannica.com/science/pituitary-gland pituitary gland]. | ||
The Human Growth Hormone, a protein circulating in the blood, has its origin on chromosome 17. There it gets encoded by the Growth hormone 1 gene along with four other related genes. Three of these genes are encoding [https://en.wikipedia.org/wiki/Human_placental_lactogen human chorionic somatomammotropin], which is closely related to somatotropin. They are all in the same transcriptional orientation. | The Human Growth Hormone, a protein circulating in the blood, has its origin on chromosome 17. There it gets encoded by the Growth hormone 1 gene along with four other related genes. Three of these genes are encoding [https://en.wikipedia.org/wiki/Human_placental_lactogen human chorionic somatomammotropin], which is closely related to somatotropin. They are all in the same transcriptional orientation. | ||
== Functions == | == Functions == | ||
Somatropin plays an important role in physiological environments such as: increasing muscle mass, reducing fat mass, providing the energy necessary for tissue growth, maintaining the right level of glucose and lipids ... and the development of the individual's body <ref name="ncbi">PMID:22291494</ref>. It acts directly on a cell surface or indirectly.<ref name="ncbi" /> In the second case, somatotropin stimulates tissues such as the liver, which in turn allows the synthesis and secretion of IGF-1, thus enabling the development of cell growth, tissue, bone and thus the linear growth of the individual.<ref name="britannica"> Utiger, R. D. and other Encyclopedia Britannica Contributors (1998), Insulin-like growth factor. Science, Chemistry.</ref> | Somatropin plays an important role in physiological environments such as: increasing muscle mass, reducing fat mass, providing the energy necessary for tissue growth, maintaining the right level of [https://en.wikipedia.org/wiki/Glucose glucose] and lipids ... and the development of the individual's body <ref name="ncbi">PMID:22291494</ref>. It acts directly on a cell surface or indirectly.<ref name="ncbi" /> In the second case, somatotropin stimulates tissues such as the liver, which in turn allows the synthesis and secretion of IGF-1, thus enabling the development of cell growth, tissue, bone and thus the linear growth of the individual.<ref name="britannica"> Utiger, R. D. and other Encyclopedia Britannica Contributors (1998), Insulin-like growth factor. Science, Chemistry.</ref> | ||
== Structure == | == Structure == | ||
