Sandbox Reserved 1648: Difference between revisions

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Some disease are due to an abnormality of the receptor or everywhere in the body which prevent leptin from reaching the receptor.

Obesity is partly due to the too weak uptake ~~of leptin by the receptor, the individual does not feel the feeling of satiety. Obesity is partly due to the too low absorption~~ of leptin by the receptor, the individual does not feel the feeling of satiety. Too few recipients, a mutation of the latter, or an inability for leptin to pass the blood-brain barrier are the causes of this resistance <ref>Le récepteur à la leptine et son role dans le développement de l'obésité : https://www.futura-sciences.com/sante/dossiers/medecine-recepteurs-membranaires-point-mire-medicaments-783/page/4/ </ref>.

Obesity is partly due to the too weak uptake of leptin by the receptor, the individual does not feel the feeling of satiety. Too few recipients, a mutation of the latter, or an inability for leptin to pass the blood-brain barrier are the causes of this resistance <ref>Le récepteur à la leptine et son role dans le développement de l'obésité : https://www.futura-sciences.com/sante/dossiers/medecine-recepteurs-membranaires-point-mire-medicaments-783/page/4/ </ref>.

Pregnancy diabetes would also be due to the overproduction of the receptor on the wall of the placenta, which would lead to an overproduction of leptin. The LEP-2548G / A gene is thought to increase the risk of this disease.

Sandbox Reserved 1648: Difference between revisions

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@@ Line 73: / Line 73: @@
 Some disease are due to an abnormality of the receptor or everywhere in the body which prevent leptin from reaching the receptor.
-Obesity is partly due to the too weak uptake of leptin by the receptor, the individual does not feel the feeling of satiety. Obesity is partly due to the too low absorption of leptin by the receptor, the individual does not feel the feeling of satiety. Too few recipients, a mutation of the latter, or an inability for leptin to pass the blood-brain barrier are the causes of this resistance <ref>Le récepteur à la leptine et son role dans le développement de l'obésité : https://www.futura-sciences.com/sante/dossiers/medecine-recepteurs-membranaires-point-mire-medicaments-783/page/4/ </ref>.
+Obesity is partly due to the too weak uptake of leptin by the receptor, the individual does not feel the feeling of satiety. Too few recipients, a mutation of the latter, or an inability for leptin to pass the blood-brain barrier are the causes of this resistance <ref>Le récepteur à la leptine et son role dans le développement de l'obésité : https://www.futura-sciences.com/sante/dossiers/medecine-recepteurs-membranaires-point-mire-medicaments-783/page/4/ </ref>.
 Pregnancy diabetes would also be due to the overproduction of the receptor on the wall of the placenta, which would lead to an overproduction of leptin. The LEP-2548G / A gene is thought to increase the risk of this disease.