Sandbox Reserved 1650: Difference between revisions

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== Synthesis ==
== Synthesis ==
=== Role and composition of the thyroid gland ===
=== Role and composition of the thyroid gland ===
The thyroid gland is an endocrine organ located in the neck that secretes HT into the bloodstream. Among them, T4 and T3 are involved in the growth, development and regulation of the metabolism of vertebrates.
The thyroid gland is an endocrine organ located in the neck that secretes thyroid hormones into the bloodstream. Among them, T4 and T3 are involved in the growth, development and regulation of the metabolism of vertebrates.


The thyroid gland is made up of thyroid vesicles, which are made up of thyroid follicular cells that are arranged around a lumen containing a viscous substance called colloid. The diet is a source of iodide I- ions which, once in the blood, are picked up by the thyroid cells and then partly discharged into the colloid.
The thyroid gland is made up of thyroid vesicles, which are made up of thyroid follicular cells that are arranged around a lumen containing a viscous substance called colloid. The diet is a source of iodide I- ions which, once in the blood, are picked up by the thyroid cells and then partly discharged into the colloid.
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<scene name='86/868183/Ntd/3'>N-terminal Domain</scene> [[https://www.youtube.com/watch?v=MuFHlCZCetU&list=PLMGnv0h7EIJydYifu7JSxrkXMzpwlkyDF&index=5>NTD]], <scene name='86/868183/Core/2'>Core</scene> [[https://www.youtube.com/watch?v=Lx1G1KGxKN8&list=PLMGnv0h7EIJydYifu7JSxrkXMzpwlkyDF&index=8>CORE]], <scene name='86/868183/Flap/1'>Flap</scene> [[https://www.youtube.com/watch?v=vk60Rdyo28A&list=PLMGnv0h7EIJydYifu7JSxrkXMzpwlkyDF&index=6>FLAP]], <scene name='86/868183/Arm/1'>Arm</scene> [[https://www.youtube.com/watch?v=XzeTjQKfO0E&list=PLMGnv0h7EIJydYifu7JSxrkXMzpwlkyDF&index=9>ARM]] and <scene name='86/868183/Ctd/1'>C-terminal Domain</scene> [[https://www.youtube.com/watch?v=N-mg_xj-deI&list=PLMGnv0h7EIJydYifu7JSxrkXMzpwlkyDF&index=7>CTD]].
<scene name='86/868183/Ntd/3'>N-terminal Domain</scene> [[https://www.youtube.com/watch?v=MuFHlCZCetU&list=PLMGnv0h7EIJydYifu7JSxrkXMzpwlkyDF&index=5>NTD]], <scene name='86/868183/Core/2'>Core</scene> [[https://www.youtube.com/watch?v=Lx1G1KGxKN8&list=PLMGnv0h7EIJydYifu7JSxrkXMzpwlkyDF&index=8>CORE]], <scene name='86/868183/Flap/1'>Flap</scene> [[https://www.youtube.com/watch?v=vk60Rdyo28A&list=PLMGnv0h7EIJydYifu7JSxrkXMzpwlkyDF&index=6>FLAP]], <scene name='86/868183/Arm/1'>Arm</scene> [[https://www.youtube.com/watch?v=XzeTjQKfO0E&list=PLMGnv0h7EIJydYifu7JSxrkXMzpwlkyDF&index=9>ARM]] and <scene name='86/868183/Ctd/1'>C-terminal Domain</scene> [[https://www.youtube.com/watch?v=N-mg_xj-deI&list=PLMGnv0h7EIJydYifu7JSxrkXMzpwlkyDF&index=7>CTD]].
   
   
In addition, TG has about 120 cysteine residues allowing the formation of about 60 disulfide bridge bonds per monomer [[https://www.youtube.com/watch?v=Nuryu1aSqvY&list=PLMGnv0h7EIJydYifu7JSxrkXMzpwlkyDF&index=11>Disulfide bridge]]. It is therefore a very stable and soluble protein.
In addition, TG has about 120 <scene name='86/868183/Cysteine/1'>cysteine residues</scene> allowing the formation of about 60 disulfide bridge bonds per monomer [[https://www.youtube.com/watch?v=Nuryu1aSqvY&list=PLMGnv0h7EIJydYifu7JSxrkXMzpwlkyDF&index=11>Disulfide bridge]]. It is therefore a very stable and soluble protein.


=== Post-translational modifications ===
=== Post-translational modifications ===
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