Sandbox Reserved 1660: Difference between revisions
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CD1d protein is made of 2 chains<ref name="Structure">Information, N. C. for B.; Pike, U. S. N. L. of M. R.; BethesdaMD; 20894USA. 3GMQ: Structure of mouse CD1d expressed in SF9 cells, no ligand added https://www.ncbi.nlm.nih.gov/Structure/pdb/3GMQ (accessed Dec 5, 2020).</ref>: <br> | CD1d protein is made of 2 chains<ref name="Structure">Information, N. C. for B.; Pike, U. S. N. L. of M. R.; BethesdaMD; 20894USA. 3GMQ: Structure of mouse CD1d expressed in SF9 cells, no ligand added https://www.ncbi.nlm.nih.gov/Structure/pdb/3GMQ (accessed Dec 5, 2020).</ref>: <br> | ||
::- an <scene name='86/868193/Alpha_chain/3'>alpha chain</scene> (T-cell surface glycoprotein CD1d1) of 287 amino acids <br> | ::- an <scene name='86/868193/Alpha_chain/3'>alpha chain</scene> (T-cell surface glycoprotein CD1d1) of 287 amino acids <br> | ||
::- a <scene name='86/868193/Beta-2-microglobulin_chain/2'>beta-2-microglobulin chain</scene> of 99 amino acids | ::- a <scene name='86/868193/Beta-2-microglobulin_chain/2'>beta-2-microglobulin chain</scene> of 99 amino acids. <br><br> | ||
The first chain is made of two [https://en.wikipedia.org/wiki/Beta_sheet beta-sheets] and a set of 2 [[alpha helix]]. Each beta-sheet contains four antiparallel strands. The total molecular weight of the alpha chain is 33 kDa when not associated to any oligosaccharide and 55 kDa when the five oligosaccharides are associated to the chain. | The first chain is made of two [https://en.wikipedia.org/wiki/Beta_sheet beta-sheets] and a set of 2 [[alpha helix]]. Each beta-sheet contains four antiparallel strands. The total molecular weight of the alpha chain is 33 kDa when not associated to any oligosaccharide and 55 kDa when the five oligosaccharides are associated to the chain. | ||
The ligand binds between the two alpha-helices. | The ligand binds between the two alpha-helices. | ||