Sandbox Reserved 1647: Difference between revisions

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==Introduction==

TBX21 or T-bet is a [https://en.wikipedia.org/wiki/Transcription_factor transcription factor], more precisely a [[T-box proteins]]. The DNA binding domain of T-bet has a dimer structure composes of two identical chains (<scene name='86/868180/Chain_a_bis/1'>A</scene> / <scene name='86/868180/Chain_b/1'>B</scene> ) with a total molecular weight of 76,37 kDA. This binding domain allows it to bind itself to the DNA on promotor or regulator area. The particularity of this T-box protein is that is able to link two DNA molecules with only one dimer. Moreover, it is able to link two areas of the same DNA molecules which are far from each other and thus create a chromatin loop.

TBX21 or T-bet is a [https://en.wikipedia.org/wiki/Transcription_factor transcription factor], more precisely a [[T-box proteins]]. The DNA binding domain of T-bet has a dimer structure composes of two identical chains (<scene name='86/868180/Chain_a_bis/1'>A</scene> / <scene name='86/868180/Chain_b/1'>B</scene> ) with a total molecular weight of 76,37 kDA. This binding domain allows it to bind itself to the DNA on promotor or regulator area. The particularity of this T-box protein is that is able to <scene name='86/868180/Link_to_2_dna/1'>link two DNA molecules with only one dimer</scene>. Moreover, it is able to link two areas of the same DNA molecules which are far from each other and thus create a chromatin loop.

The main function of this transcription factor is to direct [https://en.wikipedia.org/wiki/T_helper_cell TH1 cells differentiation] from naive CD4+ cells. Nevertheless, the action field of T-bet is larger than classical T-box protein.

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~~== Structural highlights ==~~

This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.

</StructureSection>

== References ==

Sandbox Reserved 1647: Difference between revisions

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 <Structure load='5t1j' size='350' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' />
 ==Introduction==
-TBX21 or T-bet is a [https://en.wikipedia.org/wiki/Transcription_factor transcription factor], more precisely a [[T-box proteins]]. The DNA binding domain of T-bet has a dimer structure composes of two identical chains (<scene name='86/868180/Chain_a_bis/1'>A</scene> / <scene name='86/868180/Chain_b/1'>B</scene> ) with a total molecular weight of 76,37 kDA. This binding domain allows it to bind itself to the DNA on promotor or regulator area. The particularity of this T-box protein is that is able to link two DNA molecules with only one dimer. Moreover, it is able to link two areas of the same DNA molecules which are far from each other and thus create a chromatin loop.
+TBX21 or T-bet is a [https://en.wikipedia.org/wiki/Transcription_factor transcription factor], more precisely a [[T-box proteins]]. The DNA binding domain of T-bet has a dimer structure composes of two identical chains (<scene name='86/868180/Chain_a_bis/1'>A</scene> / <scene name='86/868180/Chain_b/1'>B</scene> ) with a total molecular weight of 76,37 kDA. This binding domain allows it to bind itself to the DNA on promotor or regulator area. The particularity of this T-box protein is that is able to <scene name='86/868180/Link_to_2_dna/1'>link two DNA molecules with only one dimer</scene>. Moreover, it is able to link two areas of the same DNA molecules which are far from each other and thus create a chromatin loop.
 The main function of this transcription factor is to direct [https://en.wikipedia.org/wiki/T_helper_cell TH1 cells differentiation] from naive CD4+ cells. Nevertheless, the action field of T-bet is larger than classical T-box protein.
@@ Line 44: / Line 44: @@
-== Structural highlights ==
-This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
 </StructureSection>
 == References ==
 <references/>