Sandbox Reserved 1648: Difference between revisions
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Leptin receptors belong to the family of [https://en.wikipedia.org/wiki/Type_I_cytokine_receptor class 1 cytokine receptors]. | Leptin receptors belong to the family of [https://en.wikipedia.org/wiki/Type_I_cytokine_receptor class 1 cytokine receptors]. | ||
The leptin receptor protein is a molecule that exists in different forms : short or long. It consists of an extracellular chain of 816 amino acids, a transmembrane domain of 23 amino acids and a cytoplasmic domain <ref> Le récepteur de la leptine appartient à la famille des récepteurs de cytokines : http://www.ipubli.inserm.fr/bitstream/handle/10608/746/1996_3_386.pdf?sequence=1 </ref> <ref> La leptine : une nouvelle hormone hypo-insulinémiante ? : http://ipubli-inserm.inist.fr/bitstream/handle/10608/532/MS_1997_10_1200.pdf?sequence=1</ref>. This cytoplasmic domain is made up of 34 amino acids for the short form of the leptin receptor and 303 amino acids for the long form. | The leptin receptor protein is a molecule that exists in different forms : short or long. It consists of an extracellular chain of 816 amino acids, a transmembrane domain of 23 amino acids and a cytoplasmic domain <ref name="1"> Le récepteur de la leptine appartient à la famille des récepteurs de cytokines : http://www.ipubli.inserm.fr/bitstream/handle/10608/746/1996_3_386.pdf?sequence=1 </ref> <ref name="2"> La leptine : une nouvelle hormone hypo-insulinémiante ? : http://ipubli-inserm.inist.fr/bitstream/handle/10608/532/MS_1997_10_1200.pdf?sequence=1</ref>. This cytoplasmic domain is made up of 34 amino acids for the short form of the leptin receptor and 303 amino acids for the long form <ref name="2">. | ||
The extracellular part is itself subdivided into 5 functional domains : | The extracellular part is itself subdivided into 5 functional domains : | ||
