2a90: Difference between revisions

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==Crystal Structure of the tandem WWE domain of Drosophila Deltex==
==Crystal Structure of the tandem WWE domain of Drosophila Deltex==
<StructureSection load='2a90' size='340' side='right' caption='[[2a90]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
<StructureSection load='2a90' size='340' side='right'caption='[[2a90]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2a90]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A90 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2A90 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2a90]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A90 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A90 FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dx ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dx ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2a90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a90 OCA], [http://pdbe.org/2a90 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2a90 RCSB], [http://www.ebi.ac.uk/pdbsum/2a90 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2a90 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a90 OCA], [https://pdbe.org/2a90 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a90 RCSB], [https://www.ebi.ac.uk/pdbsum/2a90 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a90 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DTX_DROME DTX_DROME]] Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Mainly acts as a positive regulator of Notch, but it may also act as a negative regulator, depending on the developmental and cell context. Mediates the antineural activity of Notch. May function as a ubiquitin ligase protein in the Notch pathway.<ref>PMID:7671825</ref> <ref>PMID:11719214</ref> <ref>PMID:11861487</ref>   
[[https://www.uniprot.org/uniprot/DTX_DROME DTX_DROME]] Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Mainly acts as a positive regulator of Notch, but it may also act as a negative regulator, depending on the developmental and cell context. Mediates the antineural activity of Notch. May function as a ubiquitin ligase protein in the Notch pathway.<ref>PMID:7671825</ref> <ref>PMID:11719214</ref> <ref>PMID:11861487</ref>   
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Drome]]
[[Category: Drome]]
[[Category: Large Structures]]
[[Category: Barrick, D]]
[[Category: Barrick, D]]
[[Category: Leahy, D J]]
[[Category: Leahy, D J]]
Retrieved from "https://proteopedia.org/2a90"