2ac4: Difference between revisions

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==Crystal structure of the His183Cys mutant variant of Bacillus subtilis Ferrochelatase==
==Crystal structure of the His183Cys mutant variant of Bacillus subtilis Ferrochelatase==
<StructureSection load='2ac4' size='340' side='right' caption='[[2ac4]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='2ac4' size='340' side='right'caption='[[2ac4]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ac4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_globigii"_migula_1900 "bacillus globigii" migula 1900]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AC4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AC4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ac4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_globigii"_migula_1900 "bacillus globigii" migula 1900]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AC4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AC4 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1doz|1doz]], [[2ac2|2ac2]]</td></tr>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1doz|1doz]], [[2ac2|2ac2]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hemH, hemF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Bacillus globigii" Migula 1900])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hemH, hemF ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Bacillus globigii" Migula 1900])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferrochelatase Ferrochelatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.99.1.1 4.99.1.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Ferrochelatase Ferrochelatase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.99.1.1 4.99.1.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ac4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ac4 OCA], [http://pdbe.org/2ac4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ac4 RCSB], [http://www.ebi.ac.uk/pdbsum/2ac4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ac4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ac4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ac4 OCA], [https://pdbe.org/2ac4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ac4 RCSB], [https://www.ebi.ac.uk/pdbsum/2ac4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ac4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/HEMH_BACSU HEMH_BACSU]] Catalyzes the ferrous insertion into protoporphyrin IX.  
[[https://www.uniprot.org/uniprot/HEMH_BACSU HEMH_BACSU]] Catalyzes the ferrous insertion into protoporphyrin IX.  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ac/2ac4_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ac/2ac4_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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</div>
</div>
<div class="pdbe-citations 2ac4" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2ac4" style="background-color:#fffaf0;"></div>
==See Also==
*[[Ferrochelatase 3D structures|Ferrochelatase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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[[Category: Bacillus globigii migula 1900]]
[[Category: Bacillus globigii migula 1900]]
[[Category: Ferrochelatase]]
[[Category: Ferrochelatase]]
[[Category: Large Structures]]
[[Category: Al-Karadaghi, S]]
[[Category: Al-Karadaghi, S]]
[[Category: Ferreira, G C]]
[[Category: Ferreira, G C]]