2chz: Difference between revisions
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==A pharmacological map of the PI3-K family defines a role for p110alpha in signaling: The structure of complex of phosphoinositide 3-kinase gamma with inhibitor PIK-93== | ==A pharmacological map of the PI3-K family defines a role for p110alpha in signaling: The structure of complex of phosphoinositide 3-kinase gamma with inhibitor PIK-93== | ||
<StructureSection load='2chz' size='340' side='right' | <StructureSection load='2chz' size='340' side='right'caption='[[2chz]], [[Resolution|resolution]] 2.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2chz]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2chz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CHZ FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=093:N-(5-(4-CHLORO-3-(2-HYDROXY-ETHYLSULFAMOYL)-+PHENYLTHIAZOLE-2-YL)-ACETAMIDE'>093</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=093:N-(5-(4-CHLORO-3-(2-HYDROXY-ETHYLSULFAMOYL)-+PHENYLTHIAZOLE-2-YL)-ACETAMIDE'>093</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1e8y|1e8y]], [[1e8z|1e8z]], [[1he8|1he8]], [[2a4z|2a4z]], [[2a5u|2a5u]], [[2chw|2chw]], [[2chx|2chx]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1e8y|1e8y]], [[1e8z|1e8z]], [[1he8|1he8]], [[2a4z|2a4z]], [[2a5u|2a5u]], [[2chw|2chw]], [[2chx|2chx]]</div></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2chz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2chz OCA], [https://pdbe.org/2chz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2chz RCSB], [https://www.ebi.ac.uk/pdbsum/2chz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2chz ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
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==See Also== | ==See Also== | ||
*[[Phosphoinositide 3- | *[[Phosphoinositide 3-kinase 3D structures|Phosphoinositide 3-kinase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
[[Category: Large Structures]] | |||
[[Category: Balla, A]] | [[Category: Balla, A]] | ||
[[Category: Balla, T]] | [[Category: Balla, T]] | ||
