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==Solution structure of the 4th zinc finger domain of Zinc finger protein 278==
==Solution structure of the 4th zinc finger domain of Zinc finger protein 278==
<StructureSection load='2eps' size='340' side='right' caption='[[2eps]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2eps' size='340' side='right'caption='[[2eps]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2eps]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EPS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EPS FirstGlance]. <br>
<table><tr><td colspan='2'>[[2eps]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EPS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EPS FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PATZ1, PATZ, RIAZ, ZBTB19, ZNF278, ZSG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PATZ1, PATZ, RIAZ, ZBTB19, ZNF278, ZSG ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2eps FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eps OCA], [http://pdbe.org/2eps PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2eps RCSB], [http://www.ebi.ac.uk/pdbsum/2eps PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2eps ProSAT], [http://www.topsan.org/Proteins/RSGI/2eps TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eps FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eps OCA], [https://pdbe.org/2eps PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eps RCSB], [https://www.ebi.ac.uk/pdbsum/2eps PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eps ProSAT], [https://www.topsan.org/Proteins/RSGI/2eps TOPSAN]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/PATZ1_HUMAN PATZ1_HUMAN]] Note=A chromosomal aberration involving PATZ1 is associated with small round cell sarcoma. Translocation t(1;22)(p36.1;q12) with EWSR1.  
[[https://www.uniprot.org/uniprot/PATZ1_HUMAN PATZ1_HUMAN]] Note=A chromosomal aberration involving PATZ1 is associated with small round cell sarcoma. Translocation t(1;22)(p36.1;q12) with EWSR1.  
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PATZ1_HUMAN PATZ1_HUMAN]] Transcriptional repressor.<ref>PMID:10713105</ref>   
[[https://www.uniprot.org/uniprot/PATZ1_HUMAN PATZ1_HUMAN]] Transcriptional repressor.<ref>PMID:10713105</ref>   
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Inoue, M]]
[[Category: Inoue, M]]
[[Category: Kigawa, T]]
[[Category: Kigawa, T]]
Retrieved from "https://proteopedia.org/2eps"