Sandbox GGC16: Difference between revisions
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==PU.1== | ==PU.1== | ||
<StructureSection load='1PUE' size='340' side='right' caption='Caption for this structure' scene=''> | <StructureSection load='1PUE' size='340' side='right' caption='Caption for this structure' scene=''> | ||
PU.1 is a hematopoietic transcription factor. It specifically regulates transcription of macrophage and B cell genes in stem cells, ultimately leading to cellular differentiation | PU.1 is a hematopoietic transcription factor. It specifically regulates transcription of macrophage and B cell genes in stem cells, ultimately leading to cellular differentiation. | ||
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | ||
== Name == | |||
The name PU.1 comes from the protein's binding interactions with a purine-rich DNA sequence. | |||
== Function == | == Function == | ||