Sandbox GGC16

PU.1

spinqualitylabelsall models Caption for this structure Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D PU.1 is a hematopoietic transcription factor. It specifically regulates transcription of macrophage and B cell genes in stem cells, ultimately leading to cellular differentiation. You may include any references to papers as in: the use of JSmol in Proteopedia or to the article describing Jmol to the rescue. Name The name PU.1 comes from the protein's binding interactions with a purine-rich DNA sequence. Bases at Interface Function Binding Domain Residues at the binding domain Structural highlights This is a sample scene created with SAT to color by Group, and another to make a transparent representation of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.