AlphaFold2 examples from CASP 14: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
Eric Martz (talk | contribs)
ConfirmAccount, Editor, Print3D, Tester, Bureaucrats, journal, Administrators
30,128 edits
No edit summary
Eric Martz (talk | contribs)
ConfirmAccount, Editor, Print3D, Tester, Bureaucrats, journal, Administrators
30,128 edits
No edit summary
Line 31: Line 31:
|-
|-
| 3rd Best§ || 33 || 0 || 13.37<br>† || 92/92 (100%)<br>† || 14.50<br>† || 747/748 (100%)<br>†
| 3rd Best§ || 33 || 0 || 13.37<br>† || 92/92 (100%)<br>† || 14.50<br>† || 747/748 (100%)<br>†
|-
| Rosetta<br>Server || 26 || 0 || 14.99<br>† || 92/92 (100%)<br>† ||  ||
|}
|}
:Alignments by "Magic Fit" of Swiss-PdbViewer 4.1.<br>
:Alignments by "Magic Fit" of Swiss-PdbViewer 4.1.<br>
Line 46: Line 48:


===Baker Rosetta Server Prediction for ORF8===
===Baker Rosetta Server Prediction for ORF8===
Among predictions for all ~100 CASP 14 targets, the group of David Baker [https://predictioncenter.org/casp14/zscores_final.cgi ranked second]. The Rosetta Server of the Baker group ranked 18th overall, but was the 4th ranked server<ref name="serverranks">For all targets in CASP 14, the top two servers were QUARK and Zhang-server (which were not significantly different at a Z-score sum of 62.9), followed by Zhang-CEthreader (55.9) and BAKER-ROSETTASERVER (55.3).</ref>. [https://predictioncenter.org/casp14/results.cgi?view=tables&target=T1064-D1&model=1&groups_id= For ORF8, the Rosetta Server prediction GDT_TS was 26], a bit better than the median of 23.
Among predictions for all ~100 CASP 14 targets, the group of David Baker [https://predictioncenter.org/casp14/zscores_final.cgi ranked second]. The Rosetta Server of the Baker group ranked 18th overall, but was the 4th ranked server<ref name="serverranks">For all targets in CASP 14, the top two servers were QUARK and Zhang-server (which were not significantly different at a Z-score sum of 62.9), followed by Zhang-CEthreader (55.9) and BAKER-ROSETTASERVER (55.3).</ref>. [https://predictioncenter.org/casp14/results.cgi?view=tables&target=T1064-D1&model=1&groups_id= For ORF8, the Rosetta Server prediction GDT_TS was 26], a bit better than the median of 23. The Rosetta Server's prediction for ORF8 has the two termini far apart, a substantial difference from the X-ray structure. It predicts two disulfide bonds, but neither matches the pairs of Cys residues in the actual disulfide bonds.


</StructureSection>
</StructureSection>
Retrieved from "https://proteopedia.org/AlphaFold2_examples_from_CASP_14"