AlphaFold2 examples from CASP 14: Difference between revisions
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===Top Prediction by an Automated Server=== | ===Top Prediction by an Automated Server=== | ||
Among predictions by automated servers for all ~100 CASP 14 targets, the top ranking server was QUARK from the Yang Zhang group (Univ. Michigan). For ORF8, the Zhang-TBM server made the best server prediction with a '''GDT_TS of 27'''. (The prediction by QUARK was almost as good, GDT_TS 26.) The prediction has the '''two chain termini not parallel, and the amino terminus is not a beta strand''', differing in both respects from the X-ray model. Also, '''no disulfide bonds''' are predicted. | Among predictions by automated servers for all ~100 CASP 14 targets, the top ranking server was QUARK from the Yang Zhang group (Univ. Michigan). For ORF8, the Zhang-TBM server made the best server prediction with a '''GDT_TS of 27'''. (The prediction by QUARK was almost as good, GDT_TS 26.) The prediction has the '''two chain termini not parallel, and the amino terminus is not a beta strand''', differing in both respects from the X-ray model. Also, '''no disulfide bonds''' are predicted. The structural alignment is very poor and is not shown. | ||
===Baker Rosetta Server Prediction for ORF8=== | ===Baker Rosetta Server Prediction for ORF8=== | ||
