PROTAC: Difference between revisions

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==Predicting PROTACs==
==Predicting PROTACs==
PRosettaC <ref>PRosettaC https://prosettac.weizmann.ac.il, a computational resource for the prediction of PROTAC-induced ternary complexes.</ref> is a computational protocol for the prediction of PROTAC-induced ternary complexes <ref>pmid 32976709</ref>. The protocol receives as input, two protein structures (protein target and E3 ligase), including their appropriate ligands (binders), as well as the PROTAC chemical structure in a SMILES representation, and outputs predicted models for the ternary complex.  
PRosettaC <ref>PRosettaC https://prosettac.weizmann.ac.il, a computational resource for the prediction of PROTAC-induced ternary complexes.</ref> is a computational resource for the prediction of PROTAC-induced ternary complexes <ref>pmid 32976709</ref>. The protocol receives as input, two protein structures (protein target and E3 ligase), including their appropriate ligands (binders), as well as the PROTAC chemical structure in a SMILES representation, and outputs predicted models for the ternary complex.  


==PROTACpedia==
==PROTACpedia==