PROTAC: Difference between revisions
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{| class="wikitable" | {| class="wikitable" | ||
|- | |- valign="top" | ||
! PROTAC Target | ! PROTAC Target | ||
! Structure | ! Structure | ||
|- | |- valign="top" | ||
| BRAF kinase domain | | BRAF kinase domain | ||
| [[6uuo]] | | [[6uuo]] | ||
|- | |- valign="top" | ||
| BRD9 bromodomain | | BRD9 bromodomain | ||
| [[6hm0]] | | [[6hm0]] | ||
|- | |- valign="top" | ||
| Cereblon | | Cereblon | ||
| [[6r0q]], [[6r0u]], [[6r0v]], [[6r11]], [[6r12]], [[6r13]], [[6r18]], [[6r19]], [[6r1a]], [[6r1c]], [[6r1d]], [[6r1k]], [[6r1w]], [[6r1x]] | | [[6r0q]], [[6r0u]], [[6r0v]], [[6r11]], [[6r12]], [[6r13]], [[6r18]], [[6r19]], [[6r1a]], [[6r1c]], [[6r1d]], [[6r1k]], [[6r1w]], [[6r1x]] | ||
|- | |- valign="top" | ||
| DDB1-CRBN-BRD4(BD1) | | DDB1-CRBN-BRD4(BD1) | ||
| [[6bn7]], [[6bn8]], [[6bn9]], [[6bnb]], [[6boy]] | | [[6bn7]], [[6bn8]], [[6bn9]], [[6bnb]], [[6boy]] | ||
|- | |- valign="top" | ||
| SMARCA2, SMARCA4 | | SMARCA2, SMARCA4 | ||
| [[6hr2]] | | [[6hr2]] | ||
