AlphaFold2 examples from CASP 14: Difference between revisions
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<scene name='87/875686/Morf_lin_7jx6_imf_7jtl/3'>The two X-ray structures agree very well</scene><ref name="imf">Alignment by Swiss-PdbViewer's ''iterative magic fit''. This starts with a sequence alignment-guided structural alignment, and then selects subsets of the structures to minimize the RMSD. Eight intermediate structures were generated by the [[Morphs#Linear_Morph_Server|Theis Morph Server]] by linear interpolation.</ref>. The only substantial disagreement is for a large surface loop, sequence range 48-57. See the TABLE below for [https://en.wikipedia.org/wiki/Root-mean-square_deviation_of_atomic_positions RMSD] values. | <scene name='87/875686/Morf_lin_7jx6_imf_7jtl/3'>The two X-ray structures agree very well</scene><ref name="imf">Alignment by Swiss-PdbViewer's ''iterative magic fit''. This starts with a sequence alignment-guided structural alignment, and then selects subsets of the structures to minimize the RMSD. Eight intermediate structures were generated by the [[Morphs#Linear_Morph_Server|Theis Morph Server]] by linear interpolation.</ref>. The only substantial disagreement is for a large surface loop, sequence range 48-57. See the TABLE below for [https://en.wikipedia.org/wiki/Root-mean-square_deviation_of_atomic_positions RMSD] values. | ||
===ORF8 is not a novel fold=== | |||
Less than 2% of new [[empirical structures]] have novel folds; that is, folds not aready represented in the [[PDB]]<ref name="cath2011">PMID: 21097779</ref>. | |||
===AlphaFold2 Prediction for ORF8=== | ===AlphaFold2 Prediction for ORF8=== | ||
