AlphaFold2 examples from CASP 14: Difference between revisions
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==Phage RNA polymerase== | ==Phage RNA polymerase== | ||
Our second example is a 404-residue domain within a 2,180 residue RNA polymerase, [[6vr4]], gp66 from a bacteriophage of the crAss-like group, some members of which are prevalent in the human gut<ref name="T1037" />. One host for the target-containing phage is gram-negative, aerobic bacteria ''Cellulphaga baltica'' isolated from marine microalga<ref name="cb">PMID: 10425785</ref>. CASP 14 classified this domain, | Our second example is a 404-residue domain within a 2,180 residue RNA polymerase, [[6vr4]], gp66 from a bacteriophage of the crAss-like group, some members of which are prevalent in the human gut<ref name="T1037" />. One known host for the target-containing phage is gram-negative, aerobic bacteria ''Cellulphaga baltica'' isolated from marine microalga<ref name="cb">PMID: 10425785</ref>. CASP 14 classified this domain, coded T1037, as a free modeling ("FM") target, meaning that no informative templates existed in the [[PDB]]. | ||
===X-ray crystal structure=== | |||
The crystallographic structure, not available to the prediction teams during the CASP competition, is [[6vr4]], with [[resolution]] 3.5 Å, and an Rfree "quality" of "much better than average for this resolution" (according to [[FirstGlance in Jmol]]). | |||
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