6kqb: Difference between revisions
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==A long chain secondary alcohol dehydrogenase of Micrococcus luteus== | ==A long chain secondary alcohol dehydrogenase of Micrococcus luteus== | ||
<StructureSection load='6kqb' size='340' side='right'caption='[[6kqb]]' scene=''> | <StructureSection load='6kqb' size='340' side='right'caption='[[6kqb]], [[Resolution|resolution]] 2.26Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KQB OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[6kqb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacteridium_luteum"_schroeter_1872 "bacteridium luteum" schroeter 1872]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KQB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6KQB FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[6kq9|6kq9]]</div></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GY12_10930 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1270 "Bacteridium luteum" Schroeter 1872])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6kqb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kqb OCA], [https://pdbe.org/6kqb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6kqb RCSB], [https://www.ebi.ac.uk/pdbsum/6kqb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6kqb ProSAT]</span></td></tr> | |||
</table> | </table> | ||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
Structure-based engineering of a NAD+-dependent secondary alcohol dehydrogenase from Micrococcus luteus led to a 1800-fold increase in catalytic efficiency for NADP+. Furthermore, the engineered enzymes (e.g., D37S/A38R/V39S/T15I) were successfully coupled to a NADPH-dependent Baeyer-Villiger monooxygenase from Pseudomonas putida KT2440 for redox-neutral biotransformations of C18 fatty acids into C9 chemicals. | |||
Cofactor specificity engineering of a long-chain secondary alcohol dehydrogenase from Micrococcus luteus for redox-neutral biotransformation of fatty acids.,Seo EJ, Kim HJ, Kim MJ, Kim JS, Park JB Chem Commun (Camb). 2019 Nov 28;55(96):14462-14465. doi: 10.1039/c9cc06447h. PMID:31728457<ref>PMID:31728457</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
<div class="pdbe-citations 6kqb" style="background-color:#fffaf0;"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Bacteridium luteum schroeter 1872]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Kim | [[Category: Kim, H J]] | ||
[[Category: Kim | [[Category: Kim, J S]] | ||
[[Category: Alcohol dehydrogenase]] | |||
[[Category: Oxidoreductase]] | |||
Revision as of 17:44, 10 March 2021
A long chain secondary alcohol dehydrogenase of Micrococcus luteus
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