2h6u: Difference between revisions

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==Crystal structure of 5-hydroxyisourate hydrolase (formerly known as TRP, transthyretin related protein)==
==Crystal structure of 5-hydroxyisourate hydrolase (formerly known as TRP, transthyretin related protein)==
<StructureSection load='2h6u' size='340' side='right' caption='[[2h6u]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='2h6u' size='340' side='right'caption='[[2h6u]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2h6u]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Brachidanio_rerio Brachidanio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H6U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2H6U FirstGlance]. <br>
<table><tr><td colspan='2'>[[2h6u]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Brachidanio_rerio Brachidanio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H6U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2H6U FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2h1x|2h1x]], [[1f41|1f41]]</td></tr>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2h1x|2h1x]], [[1f41|1f41]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GENEID:558664 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7955 Brachidanio rerio])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GENEID:558664 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7955 Brachidanio rerio])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydroxyisourate_hydrolase Hydroxyisourate hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.17 3.5.2.17] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Hydroxyisourate_hydrolase Hydroxyisourate hydrolase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.17 3.5.2.17] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2h6u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h6u OCA], [http://pdbe.org/2h6u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2h6u RCSB], [http://www.ebi.ac.uk/pdbsum/2h6u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2h6u ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2h6u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h6u OCA], [https://pdbe.org/2h6u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2h6u RCSB], [https://www.ebi.ac.uk/pdbsum/2h6u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2h6u ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/HIUH_DANRE HIUH_DANRE]] Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).  
[[https://www.uniprot.org/uniprot/HIUH_DANRE HIUH_DANRE]] Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Transthyretin|Transthyretin]]
*[[Transthyretin 3D structures|Transthyretin 3D structures]]
== References ==
== References ==
<references/>
<references/>
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[[Category: Brachidanio rerio]]
[[Category: Brachidanio rerio]]
[[Category: Hydroxyisourate hydrolase]]
[[Category: Hydroxyisourate hydrolase]]
[[Category: Large Structures]]
[[Category: Berni, R]]
[[Category: Berni, R]]
[[Category: Cendron, L]]
[[Category: Cendron, L]]
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