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==Crystal Structure of Thioredoxin Mutant D9E in Hexagonal (p61) Space Group==
==Crystal Structure of Thioredoxin Mutant D9E in Hexagonal (p61) Space Group==
<StructureSection load='2h70' size='340' side='right' caption='[[2h70]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='2h70' size='340' side='right'caption='[[2h70]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2h70]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H70 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2H70 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2h70]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H70 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2H70 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2trx|2trx]], [[1zzy|1zzy]], [[2fch|2fch]], [[2fd3|2fd3]], [[2h6x|2h6x]], [[2h6y|2h6y]], [[2h7z|2h7z]], [[2h71|2h71]], [[2h72|2h72]], [[2h73|2h73]], [[2h74|2h74]], [[2h75|2h75]], [[2h76|2h76]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2trx|2trx]], [[1zzy|1zzy]], [[2fch|2fch]], [[2fd3|2fd3]], [[2h6x|2h6x]], [[2h6y|2h6y]], [[2h7z|2h7z]], [[2h71|2h71]], [[2h72|2h72]], [[2h73|2h73]], [[2h74|2h74]], [[2h75|2h75]], [[2h76|2h76]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trxA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trxA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2h70 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h70 OCA], [http://pdbe.org/2h70 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2h70 RCSB], [http://www.ebi.ac.uk/pdbsum/2h70 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2h70 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2h70 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h70 OCA], [https://pdbe.org/2h70 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2h70 RCSB], [https://www.ebi.ac.uk/pdbsum/2h70 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2h70 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/THIO_ECOLI THIO_ECOLI]] Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.  
[[https://www.uniprot.org/uniprot/THIO_ECOLI THIO_ECOLI]] Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h7/2h70_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h7/2h70_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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</div>
</div>
<div class="pdbe-citations 2h70" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2h70" style="background-color:#fffaf0;"></div>
==See Also==
*[[Thioredoxin 3D structures|Thioredoxin 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Bacillus coli migula 1895]]
[[Category: Large Structures]]
[[Category: Gavira, J A]]
[[Category: Gavira, J A]]
[[Category: Godoy-Ruiz, R]]
[[Category: Godoy-Ruiz, R]]
Retrieved from "https://proteopedia.org/2h70"