AlphaFold2 examples from CASP 14: Difference between revisions
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GDT_TS values for 7JTL and 5A2F vs. 7JX6 chain A were calculated using the [http://linum.proteinmodel.org/ AS2TS server] of Adam Zemla<ref name="zemla">PMID: 12824330</ref>. See instructions for [[Calculating GDT_TS]]. GDT_TS values were corrected for 92 residues (not 104) because the CASP 14 target had only 92 residues<ref name="casp14domains" />. | GDT_TS values for 7JTL and 5A2F vs. 7JX6 chain A were calculated using the [http://linum.proteinmodel.org/ AS2TS server] of Adam Zemla<ref name="zemla">PMID: 12824330</ref>. See instructions for [[Calculating GDT_TS]]. GDT_TS values were corrected for 92 residues (not 104) because the CASP 14 target had only 92 residues<ref name="casp14domains" />. | ||
For comparison, CASP 14 reported GDT_TS 86.96 for the AlphaFold2 prediction, while the AS2TS server calculated GDT_TS 85.87 vs. 7jx6 chain A, and 88.32 vs. 7JTL chain A. Thus, there appears to be some minor discrepancy between the GDT_TS calculations of CASP-14 vs. the method detailed at [[Calculating GDT_TS]]. | For comparison, CASP 14 reported GDT_TS 86.96 for the AlphaFold2 prediction, while the AS2TS server calculated GDT_TS 85.87 vs. 7jx6 chain A, and 88.32 vs. 7JTL chain A. (These results were corrected for 90/92 and 91/92 residues, respectively.) Thus, there appears to be some unidentified minor discrepancy between the GDT_TS calculations of CASP-14 vs. the method detailed at [[Calculating GDT_TS]]. | ||
==References & Notes== | ==References & Notes== | ||
<references /> | <references /> | ||
