1ft3: Difference between revisions

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== Structural highlights ==

<table><tr><td colspan='2'>[[1ft3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FT3 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1FT3 FirstGlance]. <br>

<table><tr><td colspan='2'>[[1ft3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FT3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FT3 FirstGlance]. <br>

</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1fso|1fso]], [[1fst|1fst]], [[1ft0|1ft0]]</td></tr>

</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1fso|1fso]], [[1fst|1fst]], [[1ft0|1ft0]]</div></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1ft3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ft3 OCA], [~~http~~://pdbe.org/1ft3 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1ft3 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1ft3 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1ft3 ProSAT]</span></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ft3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ft3 OCA], [https://pdbe.org/1ft3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ft3 RCSB], [https://www.ebi.ac.uk/pdbsum/1ft3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ft3 ProSAT]</span></td></tr>

</table>

== Function ==

[[~~http~~://www.uniprot.org/uniprot/GDIR1_HUMAN GDIR1_HUMAN]] Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. In glioma cells, inhibits cell migration and invasion by mediating the signals of SEMA5A and PLXNB3 that lead to inactivation of RAC1 (By similarity).

[[https://www.uniprot.org/uniprot/GDIR1_HUMAN GDIR1_HUMAN]] Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. In glioma cells, inhibits cell migration and invasion by mediating the signals of SEMA5A and PLXNB3 that lead to inactivation of RAC1 (By similarity).

== Evolutionary Conservation ==

[[Image:Consurf_key_small.gif|200px|right]]

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@@ Line 3: / Line 3: @@
 <StructureSection load='1ft3' size='340' side='right'caption='[[1ft3]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1ft3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FT3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FT3 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1ft3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FT3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FT3 FirstGlance]. <br>
-</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1fso|1fso]], [[1fst|1fst]], [[1ft0|1ft0]]</td></tr>
+</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1fso|1fso]], [[1fst|1fst]], [[1ft0|1ft0]]</div></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ft3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ft3 OCA], [http://pdbe.org/1ft3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ft3 RCSB], [http://www.ebi.ac.uk/pdbsum/1ft3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ft3 ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ft3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ft3 OCA], [https://pdbe.org/1ft3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ft3 RCSB], [https://www.ebi.ac.uk/pdbsum/1ft3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ft3 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/GDIR1_HUMAN GDIR1_HUMAN]] Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. In glioma cells, inhibits cell migration and invasion by mediating the signals of SEMA5A and PLXNB3 that lead to inactivation of RAC1 (By similarity).
+[[https://www.uniprot.org/uniprot/GDIR1_HUMAN GDIR1_HUMAN]] Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. In glioma cells, inhibits cell migration and invasion by mediating the signals of SEMA5A and PLXNB3 that lead to inactivation of RAC1 (By similarity).
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]