2hky: Difference between revisions
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==NMR solution structure of human RNase 7== | ==NMR solution structure of human RNase 7== | ||
<StructureSection load='2hky' size='340' side='right' caption='[[2hky]], [[NMR_Ensembles_of_Models | 15 NMR models]]' scene=''> | <StructureSection load='2hky' size='340' side='right'caption='[[2hky]], [[NMR_Ensembles_of_Models | 15 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2hky]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2hky]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HKY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HKY FirstGlance]. <br> | ||
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RNASE7 ([ | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RNASE7 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hky OCA], [https://pdbe.org/2hky PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hky RCSB], [https://www.ebi.ac.uk/pdbsum/2hky PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hky ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/RNAS7_HUMAN RNAS7_HUMAN]] Exhibits a potent RNase activity. Has broad-spectrum antimicrobial activity against many pathogenic microorganisms and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium.<ref>PMID:12244054</ref> <ref>PMID:12527768</ref> <ref>PMID:17150966</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
*[[Ribonuclease|Ribonuclease | *[[Ribonuclease 3D structures|Ribonuclease 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
[[Category: Large Structures]] | |||
[[Category: Chen, C]] | [[Category: Chen, C]] | ||
[[Category: Huang, Y C]] | [[Category: Huang, Y C]] | ||