2hnu: Difference between revisions

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==Crystal Structure of a Dipeptide Complex of Bovine Neurophysin-I==
==Crystal Structure of a Dipeptide Complex of Bovine Neurophysin-I==
<StructureSection load='2hnu' size='340' side='right' caption='[[2hnu]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='2hnu' size='340' side='right'caption='[[2hnu]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2hnu]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HNU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HNU FirstGlance]. <br>
<table><tr><td colspan='2'>[[2hnu]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HNU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HNU FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PHE:PHENYLALANINE'>PHE</scene>, <scene name='pdbligand=TYR:TYROSINE'>TYR</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PHE:PHENYLALANINE'>PHE</scene>, <scene name='pdbligand=TYR:TYROSINE'>TYR</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2hnv|2hnv]], [[2hnw|2hnw]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2hnv|2hnv]], [[2hnw|2hnw]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">OXT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9913 BOVIN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">OXT ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9913 BOVIN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hnu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hnu OCA], [http://pdbe.org/2hnu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2hnu RCSB], [http://www.ebi.ac.uk/pdbsum/2hnu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2hnu ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hnu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hnu OCA], [https://pdbe.org/2hnu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hnu RCSB], [https://www.ebi.ac.uk/pdbsum/2hnu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hnu ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/NEU1_BOVIN NEU1_BOVIN]] Neurophysin 1 specifically binds oxytocin.  Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland.  
[[https://www.uniprot.org/uniprot/NEU1_BOVIN NEU1_BOVIN]] Neurophysin 1 specifically binds oxytocin.  Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland.  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hn/2hnu_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hn/2hnu_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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</StructureSection>
</StructureSection>
[[Category: Bovin]]
[[Category: Bovin]]
[[Category: Large Structures]]
[[Category: Breslow, E]]
[[Category: Breslow, E]]
[[Category: Lee, H]]
[[Category: Lee, H]]
Retrieved from "https://proteopedia.org/2hnu"