1hp3: Difference between revisions

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== Structural highlights ==

<table><tr><td colspan='2'>[[1hp3]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HP3 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1HP3 FirstGlance]. <br>

<table><tr><td colspan='2'>[[1hp3]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HP3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HP3 FirstGlance]. <br>

</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1g9p|1g9p]]</td></tr>

</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1g9p|1g9p]]</div></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1hp3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hp3 OCA], [~~http~~://pdbe.org/1hp3 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1hp3 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1hp3 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1hp3 ProSAT]</span></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hp3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hp3 OCA], [https://pdbe.org/1hp3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hp3 RCSB], [https://www.ebi.ac.uk/pdbsum/1hp3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hp3 ProSAT]</span></td></tr>

</table>

== Function ==

[[~~http~~://www.uniprot.org/uniprot/TOT2A_HADVE TOT2A_HADVE]] Potent inhibitor of insect (bee brain), but not mammalian (rat trigeminal neurons), voltage-gated calcium channels (Cav). As for omega-AcTx-Hv1a, the phenotypic effect of injection of this toxin into lone star ticks (Amblyomma americanum) is curling of all eight legs into closed loops, followed by death.<ref>PMID:16330063</ref>

[[https://www.uniprot.org/uniprot/TOT2A_HADVE TOT2A_HADVE]] Potent inhibitor of insect (bee brain), but not mammalian (rat trigeminal neurons), voltage-gated calcium channels (Cav). As for omega-AcTx-Hv1a, the phenotypic effect of injection of this toxin into lone star ticks (Amblyomma americanum) is curling of all eight legs into closed loops, followed by death.<ref>PMID:16330063</ref>

== Publication Abstract from PubMed ==

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 <StructureSection load='1hp3' size='340' side='right'caption='[[1hp3]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1hp3]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HP3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HP3 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1hp3]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HP3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HP3 FirstGlance]. <br>
-</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1g9p|1g9p]]</td></tr>
+</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1g9p|1g9p]]</div></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hp3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hp3 OCA], [http://pdbe.org/1hp3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1hp3 RCSB], [http://www.ebi.ac.uk/pdbsum/1hp3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1hp3 ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hp3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hp3 OCA], [https://pdbe.org/1hp3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hp3 RCSB], [https://www.ebi.ac.uk/pdbsum/1hp3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hp3 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/TOT2A_HADVE TOT2A_HADVE]] Potent inhibitor of insect (bee brain), but not mammalian (rat trigeminal neurons), voltage-gated calcium channels (Cav). As for omega-AcTx-Hv1a, the phenotypic effect of injection of this toxin into lone star ticks (Amblyomma americanum) is curling of all eight legs into closed loops, followed by death.<ref>PMID:16330063</ref>
+[[https://www.uniprot.org/uniprot/TOT2A_HADVE TOT2A_HADVE]] Potent inhibitor of insect (bee brain), but not mammalian (rat trigeminal neurons), voltage-gated calcium channels (Cav). As for omega-AcTx-Hv1a, the phenotypic effect of injection of this toxin into lone star ticks (Amblyomma americanum) is curling of all eight legs into closed loops, followed by death.<ref>PMID:16330063</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==