2krn: Difference between revisions
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==High resolution structure of the second SH3 domain of CD2AP== | ==High resolution structure of the second SH3 domain of CD2AP== | ||
<StructureSection load='2krn' size='340' side='right' caption='[[2krn]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''> | <StructureSection load='2krn' size='340' side='right'caption='[[2krn]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2krn]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2krn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KRN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KRN FirstGlance]. <br> | ||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2fei|2fei]], [[2jte|2jte]], [[2o2o|2o2o]], [[3krm|3krm]], [[3kro|3kro]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2fei|2fei]], [[2jte|2jte]], [[2o2o|2o2o]], [[3krm|3krm]], [[3kro|3kro]]</div></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cd2ap, Mets1 ([ | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cd2ap, Mets1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2krn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2krn OCA], [https://pdbe.org/2krn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2krn RCSB], [https://www.ebi.ac.uk/pdbsum/2krn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2krn ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/CD2AP_MOUSE CD2AP_MOUSE]] Required for cytokinesis (By similarity). Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus.<ref>PMID:10514378</ref> | ||
==See Also== | ==See Also== | ||
*[[CD2-associated protein|CD2-associated protein]] | *[[CD2-associated protein 3D structures|CD2-associated protein 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Lk3 transgenic mice]] | [[Category: Lk3 transgenic mice]] | ||
[[Category: Azuaga, A I]] | [[Category: Azuaga, A I]] | ||
