2kw3: Difference between revisions

<StructureSection load='2kw3' size='340' side='right' caption='[[2kw3]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>

<table><tr><td colspan='2'>[[2kw3]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KW3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KW3 FirstGlance]. <br>

</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RFX5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), RFXAP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kw3 OCA], [http://pdbe.org/2kw3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2kw3 RCSB], [http://www.ebi.ac.uk/pdbsum/2kw3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2kw3 ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/RFX5_HUMAN RFX5_HUMAN]] Immunodeficiency by defective expression of HLA class 2. The disease is caused by mutations affecting the gene represented in this entry. [[http://www.uniprot.org/uniprot/RFXAP_HUMAN RFXAP_HUMAN]] Immunodeficiency by defective expression of HLA class 2. The disease is caused by mutations affecting the gene represented in this entry.  

[[http://www.uniprot.org/uniprot/RFX5_HUMAN RFX5_HUMAN]] Activates transcription from class II MHC promoters. Recognizes X-boxes. Mediates cooperative binding between RFX and NF-Y. RFX binds the X1 box of MHC-II promoters. [[http://www.uniprot.org/uniprot/RFXAP_HUMAN RFXAP_HUMAN]] Part of the RFX complex that binds to the X-box of MHC II promoters.