1e9n: Difference between revisions

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[[Image:1e9n.jpg|left|200px]]
[[Image:1e9n.jpg|left|200px]]


{{Structure
<!--
|PDB= 1e9n |SIZE=350|CAPTION= <scene name='initialview01'>1e9n</scene>, resolution 2.2&Aring;
The line below this paragraph, containing "STRUCTURE_1e9n", creates the "Structure Box" on the page.
|SITE= <scene name='pdbsite=PB1:Pb+Binding+Site+For+Residue+A1319'>PB1</scene>, <scene name='pdbsite=PB2:Pb+Binding+Site+For+Residue+A1320'>PB2</scene>, <scene name='pdbsite=PB3:Pb+Binding+Site+For+Residue+B1319'>PB3</scene> and <scene name='pdbsite=PB4:Pb+Binding+Site+For+Residue+B1320'>PB4</scene>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
|LIGAND= <scene name='pdbligand=PB:LEAD+(II)+ION'>PB</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-(apurinic_or_apyrimidinic_site)_lyase DNA-(apurinic or apyrimidinic site) lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.99.18 4.2.99.18] </span>
or leave the SCENE parameter empty for the default display.
|GENE= APE1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
-->
|DOMAIN=
{{STRUCTURE_1e9n| PDB=1e9n  | SCENE= }}  
|RELATEDENTRY=
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1e9n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e9n OCA], [http://www.ebi.ac.uk/pdbsum/1e9n PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1e9n RCSB]</span>
}}


'''A SECOND DIVALENT METAL ION IN THE ACTIVE SITE OF A NEW CRYSTAL FORM OF HUMAN APURINIC/APYRIMIDINIC ENDONUCLEASE, APE1, AND ITS IMPLICATIONS FOR THE CATALYTIC MECHANISM'''
'''A SECOND DIVALENT METAL ION IN THE ACTIVE SITE OF A NEW CRYSTAL FORM OF HUMAN APURINIC/APYRIMIDINIC ENDONUCLEASE, APE1, AND ITS IMPLICATIONS FOR THE CATALYTIC MECHANISM'''
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==Reference==
==Reference==
Two divalent metal ions in the active site of a new crystal form of human apurinic/apyrimidinic endonuclease, Ape1: implications for the catalytic mechanism., Beernink PT, Segelke BW, Hadi MZ, Erzberger JP, Wilson DM 3rd, Rupp B, J Mol Biol. 2001 Apr 6;307(4):1023-34. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11286553 11286553]
Two divalent metal ions in the active site of a new crystal form of human apurinic/apyrimidinic endonuclease, Ape1: implications for the catalytic mechanism., Beernink PT, Segelke BW, Hadi MZ, Erzberger JP, Wilson DM 3rd, Rupp B, J Mol Biol. 2001 Apr 6;307(4):1023-34. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11286553 11286553]
[[Category: DNA-(apurinic or apyrimidinic site) lyase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: Rupp, B.]]
[[Category: Rupp, B.]]
[[Category: Segelke, B W.]]
[[Category: Segelke, B W.]]
[[Category: abasic endonuclease]]
[[Category: Abasic endonuclease]]
[[Category: alpha]]
[[Category: Alpha]]
[[Category: ape1]]
[[Category: Ape1]]
[[Category: base excision repair]]
[[Category: Base excision repair]]
[[Category: beta sandwich]]
[[Category: Beta sandwich]]
[[Category: dna repair endonuclease]]
[[Category: Dna repair endonuclease]]
[[Category: hap1]]
[[Category: Hap1]]
[[Category: ref-1]]
[[Category: Ref-1]]
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:58:08 2008''