Isopeptide bond: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Eric Martz (talk | contribs) |
Eric Martz (talk | contribs) |
||
| Line 32: | Line 32: | ||
==Examples== | ==Examples== | ||
===Specified=== | |||
Isopeptide bonds in the following examples are specified in LINK/_struct_conn records. | |||
*The capsid of the HK97 bacteriophage contains isopeptide bonds that cross-link the protein [[chains]] into a protein ''chain mail'' <ref>PMID: 22297521</ref><ref>PMID: 10572124</ref><ref name="wikoff2000">PMID: 19091865</ref>. However, these do not occur in the [[asymmetric unit]] of [[1ohg]]<ref>PMID: 11000116</ref>. They can be visualized in the [[biological unit]], which is the full virus capsid, but that is technically challenging. | *The capsid of the HK97 bacteriophage contains isopeptide bonds that cross-link the protein [[chains]] into a protein ''chain mail'' <ref>PMID: 22297521</ref><ref>PMID: 10572124</ref><ref name="wikoff2000">PMID: 19091865</ref>. However, these do not occur in the [[asymmetric unit]] of [[1ohg]]<ref>PMID: 11000116</ref>. They can be visualized in the [[biological unit]], which is the full virus capsid, but that is technically challenging. | ||
* [[7cap]] is a ubiquitin homotrimer. The C-terminal Gly76 is isopeptide linked to Lys48 in each inter-chain interface<ref>PMID: 32731397</ref>. | * [[7cap]] is a ubiquitin homotrimer. The C-terminal Gly76 is isopeptide linked to Lys48 in each inter-chain interface<ref>PMID: 32731397</ref>. | ||
* [[4mli]] contains the SpyTag peptide (which can be linked to a protein of interest) forming an isopeptide bond between SpyTag peptide Lys31 and SpyCatcher protein Asp117<ref>PMID: 24161952</ref>. | * [[4mli]] contains the SpyTag peptide (which can be linked to a protein of interest) forming an isopeptide bond between SpyTag peptide Lys31 and SpyCatcher protein Asp117<ref>PMID: 24161952</ref>. | ||
* [[3htl]] is a pilus monomer with isopepide bonds Lys199-Asn321 and Lys363-Asn482<ref>PMID: 19805181</ref>. | * [[3htl]] is a pilus monomer with isopepide bonds Lys199-Asn321 and Lys363-Asn482<ref>PMID: 19805181</ref>. | ||
===Unspecified=== | |||
Isopeptide bonds in the following examples are '''not''' specified in LINK/_struct_conn records. | |||
*[[1fma]]: Lys118 chain E to the carboxy-terminal Gly81 in chain D. | |||
*[[5jqf]]: Asp9 to the amino terminus at Gly1. | |||
==Visualization== | ==Visualization== | ||