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==Solution NMR structure of SH3 domain of growth arrest-specific protein 7 (GAS7) (fragment 1-60) from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8574A==
==Solution NMR structure of SH3 domain of growth arrest-specific protein 7 (GAS7) (fragment 1-60) from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8574A==
<StructureSection load='2lx7' size='340' side='right' caption='[[2lx7]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2lx7' size='340' side='right'caption='[[2lx7]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2lx7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LX7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LX7 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2lx7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LX7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LX7 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GAS7, KIAA0394 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GAS7, KIAA0394 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lx7 OCA], [http://pdbe.org/2lx7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lx7 RCSB], [http://www.ebi.ac.uk/pdbsum/2lx7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2lx7 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lx7 OCA], [https://pdbe.org/2lx7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lx7 RCSB], [https://www.ebi.ac.uk/pdbsum/2lx7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lx7 ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/GAS7_HUMAN GAS7_HUMAN]] Note=A chromosomal aberration involving GAS7 is found in acute myeloid leukemia. Translocation t(11;17)(q23;p13) with MLL/HRX.  
[[https://www.uniprot.org/uniprot/GAS7_HUMAN GAS7_HUMAN]] Note=A chromosomal aberration involving GAS7 is found in acute myeloid leukemia. Translocation t(11;17)(q23;p13) with MLL/HRX.  
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GAS7_HUMAN GAS7_HUMAN]] May play a role in promoting maturation and morphological differentiation of cerebellar neurons.  
[[https://www.uniprot.org/uniprot/GAS7_HUMAN GAS7_HUMAN]] May play a role in promoting maturation and morphological differentiation of cerebellar neurons.  
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Acton, T]]
[[Category: Acton, T]]
[[Category: Dan, L]]
[[Category: Dan, L]]
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