2o7v: Difference between revisions

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==Carboxylesterase AeCXE1 from Actinidia eriantha covalently inhibited by paraoxon==
==Carboxylesterase AeCXE1 from Actinidia eriantha covalently inhibited by paraoxon==
<StructureSection load='2o7v' size='340' side='right' caption='[[2o7v]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='2o7v' size='340' side='right'caption='[[2o7v]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2o7v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Acter Acter]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O7V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2O7V FirstGlance]. <br>
<table><tr><td colspan='2'>[[2o7v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Acter Acter]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O7V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O7V FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DEP:DIETHYL+PHOSPHONATE'>DEP</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DEP:DIETHYL+PHOSPHONATE'>DEP</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2o7r|2o7r]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2o7r|2o7r]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CXE1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=165200 ACTER])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CXE1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=165200 ACTER])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carboxylesterase Carboxylesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.1 3.1.1.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Carboxylesterase Carboxylesterase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.1 3.1.1.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2o7v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o7v OCA], [http://pdbe.org/2o7v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2o7v RCSB], [http://www.ebi.ac.uk/pdbsum/2o7v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2o7v ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o7v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o7v OCA], [https://pdbe.org/2o7v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o7v RCSB], [https://www.ebi.ac.uk/pdbsum/2o7v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o7v ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CXE1_ACTER CXE1_ACTER]] Carboxylesterase acting on esters with varying acyl chain length.<ref>PMID:17256879</ref>   
[[https://www.uniprot.org/uniprot/CXE1_ACTER CXE1_ACTER]] Carboxylesterase acting on esters with varying acyl chain length.<ref>PMID:17256879</ref>   
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o7/2o7v_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o7/2o7v_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
*[[Carboxylesterase|Carboxylesterase]]
*[[Carboxylesterase 3D structures|Carboxylesterase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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[[Category: Acter]]
[[Category: Acter]]
[[Category: Carboxylesterase]]
[[Category: Carboxylesterase]]
[[Category: Large Structures]]
[[Category: Baker, E N]]
[[Category: Baker, E N]]
[[Category: Baker, H M]]
[[Category: Baker, H M]]