Cruzain: Difference between revisions
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<StructureSection load='1me3' size='350' side='right' caption='Structure of cruzain catalytic domain complex with methylketone inhibitor (PDB entry [[1me3]])' scene='51/517378/Cv/1'> | <StructureSection load='1me3' size='350' side='right' caption='Structure of cruzain catalytic domain complex with methylketone inhibitor (PDB entry [[1me3]])' scene='51/517378/Cv/1'> | ||
'''Cruzain''' or ''' | '''Cruzain''' or '''cruzipain''' (Cru) is the major cysteine protease present in ''Trypanosoma cruzi'' which is the parasite causing Chagas disease. <ref>PMID:10997902</ref> | ||
== Relevance == | == Relevance == | ||
Revision as of 07:50, 13 June 2021
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3D structures of cruzain
Updated on 13-June-2021
1me3, 2aim, 1me3, 1me4 – Cru catalytic domain + methylketone inhibitor – Trypanosoma cruzi
1f29, 1f2a, 1f2b, 1f2c, 1ewo, 3lxs - Cru catalytic domain + vinyl sulfone derived inhibitor
1ewl, 1ewm – Cru catalytic domain + methylbutane inhibitor
1ewp - Cru catalytic domain + MOR-Leu-HPQ
4w5b, 4xui, 4qh6, 4pi3, 4klb, 3kku, 3i06, 2oz2, 1u9q – TcPRO + inhibitor
4w5c, 3iut, 3hd3 – TcPRO (mutant) + inhibitor
