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==Crystal structure of the C-terminal domain of protein MJ0236 (Y236_METJA)==
==Crystal structure of the C-terminal domain of protein MJ0236 (Y236_METJA)==
<StructureSection load='2php' size='340' side='right' caption='[[2php]], [[Resolution|resolution]] 2.03&Aring;' scene=''>
<StructureSection load='2php' size='340' side='right'caption='[[2php]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2php]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Metja Metja]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PHP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PHP FirstGlance]. <br>
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PHP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PHP FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2php FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2php OCA], [https://pdbe.org/2php PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2php RCSB], [https://www.ebi.ac.uk/pdbsum/2php PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2php ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2php TOPSAN]</span></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2pb9|2pb9]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MJ0236 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243232 METJA])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2php FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2php OCA], [http://pdbe.org/2php PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2php RCSB], [http://www.ebi.ac.uk/pdbsum/2php PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2php ProSAT], [http://www.topsan.org/Proteins/NYSGXRC/2php TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/THIDN_METJA THIDN_METJA]] Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.  Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Metja]]
[[Category: Large Structures]]
[[Category: Burley, S K]]
[[Category: Burley SK]]
[[Category: Eswaramoorthy, S]]
[[Category: Eswaramoorthy S]]
[[Category: Structural genomic]]
[[Category: Swaminathan S]]
[[Category: Swaminathan, S]]
[[Category: Chlorine ion]]
[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
[[Category: PSI, Protein structure initiative]]
[[Category: Unknown function]]
Retrieved from "https://proteopedia.org/2php"