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==Pentamer Structure of Major Capsid protein L1 of Human Papilloma Virus Type 35==
==Pentamer Structure of Major Capsid protein L1 of Human Papilloma Virus Type 35==
<StructureSection load='2r5j' size='340' side='right' caption='[[2r5j]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
<StructureSection load='2r5j' size='340' side='right'caption='[[2r5j]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2r5j]] is a 15 chain structure with sequence from [http://en.wikipedia.org/wiki/Hpv35 Hpv35]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R5J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2R5J FirstGlance]. <br>
<table><tr><td colspan='2'>[[2r5j]] is a 15 chain structure with sequence from [https://en.wikipedia.org/wiki/Hpv35 Hpv35]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R5J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R5J FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2r5h|2r5h]], [[2r5i|2r5i]], [[2r5k|2r5k]]</td></tr>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2r5h|2r5h]], [[2r5i|2r5i]], [[2r5k|2r5k]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">L1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10587 HPV35])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">L1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10587 HPV35])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2r5j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r5j OCA], [http://pdbe.org/2r5j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2r5j RCSB], [http://www.ebi.ac.uk/pdbsum/2r5j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2r5j ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r5j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r5j OCA], [https://pdbe.org/2r5j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r5j RCSB], [https://www.ebi.ac.uk/pdbsum/2r5j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r5j ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/VL1_HPV35 VL1_HPV35]] Forms an icosahedral capsid with a T=7 symmetry and about 55 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. The capsid encapsulates the genomic DNA, but does not bind DNA. Essential for the initial attachment to the host cell (By similarity).  
[[https://www.uniprot.org/uniprot/VL1_HPV35 VL1_HPV35]] Forms an icosahedral capsid with a T=7 symmetry and about 55 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. The capsid encapsulates the genomic DNA, but does not bind DNA. Essential for the initial attachment to the host cell (By similarity).  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r5/2r5j_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r5/2r5j_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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</div>
</div>
<div class="pdbe-citations 2r5j" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2r5j" style="background-color:#fffaf0;"></div>
==See Also==
*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Hpv35]]
[[Category: Hpv35]]
[[Category: Large Structures]]
[[Category: Bishop, B]]
[[Category: Bishop, B]]
[[Category: Chen, X S]]
[[Category: Chen, X S]]
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