2vfa: Difference between revisions

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<StructureSection load='2vfa' size='340' side='right'caption='[[2vfa]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='2vfa' size='340' side='right'caption='[[2vfa]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2vfa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plafg Plafg]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VFA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VFA FirstGlance]. <br>
<table><tr><td colspan='2'>[[2vfa]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plafg Plafg]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VFA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VFA FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1z7g|1z7g]], [[1d6n|1d6n]], [[1hmp|1hmp]], [[1cjb|1cjb]], [[1bzy|1bzy]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1z7g|1z7g]], [[1d6n|1d6n]], [[1hmp|1hmp]], [[1cjb|1cjb]], [[1bzy|1bzy]]</div></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vfa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vfa OCA], [http://pdbe.org/2vfa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vfa RCSB], [http://www.ebi.ac.uk/pdbsum/2vfa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vfa ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vfa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vfa OCA], [https://pdbe.org/2vfa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vfa RCSB], [https://www.ebi.ac.uk/pdbsum/2vfa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vfa ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/HGXR_PLAFG HGXR_PLAFG]] Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Works with guanine, hypoxanthine and xanthine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway.  
[[https://www.uniprot.org/uniprot/HGXR_PLAFG HGXR_PLAFG]] Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Works with guanine, hypoxanthine and xanthine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway.  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</div>
</div>
<div class="pdbe-citations 2vfa" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2vfa" style="background-color:#fffaf0;"></div>
==See Also==
*[[Phosphoribosyltransferase|Phosphoribosyltransferase]]
== References ==
== References ==
<references/>
<references/>
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