Isopeptide bond: Difference between revisions

From Proteopedia
Jump to navigationJump to search
Eric Martz (talk | contribs)
Eric Martz (talk | contribs)
Line 47: Line 47:
* [[7cap]] is a ubiquitin homotrimer. [[3alb|3ALB]] is a ubiquitin homotetramer. In both cases, the <b>C-terminal</b> Gly76 is isopeptide linked to Lys48 in each inter-chain interface<ref name="hiranyakorn" />.
* [[7cap]] is a ubiquitin homotrimer. [[3alb|3ALB]] is a ubiquitin homotetramer. In both cases, the <b>C-terminal</b> Gly76 is isopeptide linked to Lys48 in each inter-chain interface<ref name="hiranyakorn" />.
* [[4mli]] contains the SpyTag peptide (which can be linked to a protein of interest) forming an isopeptide bond between SpyTag peptide Lys31 and SpyCatcher protein Asp117<ref>PMID: 24161952</ref>.
* [[4mli]] contains the SpyTag peptide (which can be linked to a protein of interest) forming an isopeptide bond between SpyTag peptide Lys31 and SpyCatcher protein Asp117<ref>PMID: 24161952</ref>.
* [[3htl]] is a pilus monomer with spontaneously-formed intra-chain isopeptide bonds Lys199-Asn321 and Lys363-Asn482<ref>PMID: 19805181</ref>. (Pilin chains form enzymatically, linked by the isopeptide Lys169 sidechain bonded to the carboxy terminus Thr494. Those inter-chain isopeptide bonds are not present in the monomer structure.)
* [[3htl]] is a pilus monomer with spontaneously-formed <b>intra-chain</b> isopeptide bonds Lys199-Asn321 and Lys363-Asn482<ref>PMID: 19805181</ref>. (Pilin chains form enzymatically, linked by the isopeptide Lys169 sidechain bonded to the carboxy terminus Thr494. Those inter-chain isopeptide bonds are not present in the monomer structure.)
* [[6vzx]]: triple helix formed from collagen-mimetic peptides, stabilized by Lys11-Glu13 inter-chain isopeptide bonds.
* [[6vzx]]: triple helix formed from collagen-mimetic peptides, stabilized by Lys11-Glu13 inter-chain isopeptide bonds.