1fso: Difference between revisions

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<StructureSection load='1fso' size='340' side='right'caption='[[1fso]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='1fso' size='340' side='right'caption='[[1fso]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1fso]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FSO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FSO FirstGlance]. <br>
<table><tr><td colspan='2'>[[1fso]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FSO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FSO FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1fst|1fst]], [[1ft0|1ft0]], [[1ft3|1ft3]]</td></tr>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1fst|1fst]], [[1ft0|1ft0]], [[1ft3|1ft3]]</div></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1fso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fso OCA], [http://pdbe.org/1fso PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1fso RCSB], [http://www.ebi.ac.uk/pdbsum/1fso PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1fso ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fso OCA], [https://pdbe.org/1fso PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fso RCSB], [https://www.ebi.ac.uk/pdbsum/1fso PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fso ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GDIR1_HUMAN GDIR1_HUMAN]] Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. In glioma cells, inhibits cell migration and invasion by mediating the signals of SEMA5A and PLXNB3 that lead to inactivation of RAC1 (By similarity).  
[[https://www.uniprot.org/uniprot/GDIR1_HUMAN GDIR1_HUMAN]] Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. In glioma cells, inhibits cell migration and invasion by mediating the signals of SEMA5A and PLXNB3 that lead to inactivation of RAC1 (By similarity).  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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