User:Nikhil Malvankar/Geobacter pilus structure and function: Difference between revisions

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===Other Findings and Conclusions===
===Other Findings and Conclusions===


As detailed in the journal publication, the PilA-N-C pili studied here are 50-fold less electrically conductive than the nanowires composed of cytochromes<ref name="nw1" /><ref name="nw2" />. These PilA-N-C pili lack the structural hallmarks of type 4 pili, but share structural characteristics with pseudopili.  PilA-N and PilA-C remain in the inner membrane, unless the gene for OmcS (or OmcZ) is deleted, in which case they form the pili extending outside the cell studied here. When the ''pilA-N'' gene is deleted, OmcS nanowires fail to be produced. It is proposed in the journal publication that PilA-N-C is part of a secretion system required for production of OmcS/OmcZ nanowires.
As detailed in the journal publication, the PilA-N-C pili studied here are 50-fold less electrically conductive than the nanowires composed of OmcS cytochromes<ref name="nw1" /><ref name="nw2" />, and >1,000-fold less conductive than OmcZ nanowires. These PilA-N-C pili lack the structural hallmarks of type 4 pili, but share structural characteristics with pseudopili.  PilA-N and PilA-C remain in the inner membrane, unless the gene for OmcS (or OmcZ) is deleted, in which case they form the pili extending outside the cell studied here. When the ''pilA-N'' gene is deleted, OmcS nanowires fail to be produced. It is proposed in the journal publication that PilA-N-C is part of a secretion system required for production of OmcS/OmcZ nanowires.