7p5j: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Cryo-EM structure of human TTYH1 in GDN== | ==Cryo-EM structure of human TTYH1 in GDN== | ||
<StructureSection load='7p5j' size='340' side='right'caption='[[7p5j]]' scene=''> | <StructureSection load='7p5j' size='340' side='right'caption='[[7p5j]], [[Resolution|resolution]] 4.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P5J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P5J FirstGlance]. <br> | <table><tr><td colspan='2'>[[7p5j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P5J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P5J FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p5j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p5j OCA], [https://pdbe.org/7p5j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p5j RCSB], [https://www.ebi.ac.uk/pdbsum/7p5j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p5j ProSAT]</span></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TTYH1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p5j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p5j OCA], [https://pdbe.org/7p5j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p5j RCSB], [https://www.ebi.ac.uk/pdbsum/7p5j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p5j ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[[https://www.uniprot.org/uniprot/TTYH1_HUMAN TTYH1_HUMAN]] Probable chloride channel. May be involved in cell adhesion (By similarity). Isoform 3 may be a Ca(2+)-independent and swelling-activated chloride channel, possibly involved in regulation of cell volume. | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Deneka D]] | [[Category: Deneka, D]] | ||
[[Category: Dutzler R]] | [[Category: Dutzler, R]] | ||
[[Category: Sawicka M]] | [[Category: Sawicka, M]] | ||
[[Category: Straub | [[Category: Straub, M S]] | ||
[[Category: Sukalskaia A]] | [[Category: Sukalskaia, A]] | ||
[[Category: Lipid metabolism]] | |||
[[Category: Lipid transport]] | |||
[[Category: Membrane protein]] | |||
