1snb: Difference between revisions

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<StructureSection load='1snb' size='340' side='right'caption='[[1snb]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='1snb' size='340' side='right'caption='[[1snb]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1snb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mesobuthus_martensii Mesobuthus martensii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SNB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1SNB FirstGlance]. <br>
<table><tr><td colspan='2'>[[1snb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mesobuthus_martensii Mesobuthus martensii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SNB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SNB FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1snb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1snb OCA], [http://pdbe.org/1snb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1snb RCSB], [http://www.ebi.ac.uk/pdbsum/1snb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1snb ProSAT]</span></td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1snb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1snb OCA], [https://pdbe.org/1snb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1snb RCSB], [https://www.ebi.ac.uk/pdbsum/1snb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1snb ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/SCX8_MESMA SCX8_MESMA]] Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission. This acidic toxin has a weak toxicity and is active against mammals.  
[[https://www.uniprot.org/uniprot/SCX8_MESMA SCX8_MESMA]] Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission. This acidic toxin has a weak toxicity and is active against mammals.  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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